The intent of this article is to be a step to inform stakeholders in strategies implementation to increase the level of development of our country and, therefore, interested in the well-being of the society. It is reviewed the modern model of economic development through innovation of the triple helix, which underlies the subsequent models, the quadruple helix, in the implementation of which the author has a direct involvement, the quintuple and n-tuple helix. Critical comments on these are presented in the attempt to adapt and make them applicable to the existing conditions at present in our country. There are presented concrete examples of the implementation of the helical development system through innovation at European level. Taking into account the innovative spirit of the Romanian society, expressed by the number of creative people in our country and the number and the value internationally recognized of their innovations and inventions, some sketches are proposed for the creation of economic entities for them by using helicoidal models of innovation in the perspective of their development at the level of creative, competitive and respected national and international economic institutions. Also, opinions are presented regarding the implementation of helical innovation models in order to develop economically deficient areas and to recover or reactivate the destroyed or declining economic entities.